The only detail we have of Hetty's life in Philadelphia is that she was an office of the Females Hebrew Benevolent Society.
We don't know the Samuel family's connection with Philadelphia. Three of David's siblings also emigrated to Phildelphia, Frederick, Albert and Eleanor.
David and Hetty lived in Philadelphia with their four sons and daughter. From the 1880 and 1890 Philadelphia census records it seems that Herny (a merchant) Joseph (an artist) and Eleanor (keeping house) never married. Clara married Fredrick Myers and they had one daughter, Frances. Clara died in 1860.
J Bunford Samuel married Ellen Phillips Samuel (1849 -1913). He wrote 'From Records of the Samuel Family' in 1913, which contains images for his father and mother, David and Hetty Samuel, and his grandparents Samuel and Brindella Samuel. We know from David's passport application that he was 5ft 7in, had a high forehand, hazel eyes, a prominent nose, a large mouth, full chin, black hair and a sallow complexion!
His wife, Ellen Phillips Samuels was a remarkable woman. She was a philanthropic supporter of many cultural activities in Philadelphia and when she died in 1913 left the bulk of her estate in trust to the Art Association. The Ellen Phillips memorial in Fairmount Park includes three terraces and seventeen sculptures.